log(Ne/O) as a function of 12+log(Ne/H) for SFGs of the DESIRED-E sample, which Ne/O ratios have been calculated using the ICF(Ne) scheme by Izotov et al. (2006). The red continuous line represents a linear fit to the data. The green continuous line shows the time evolution of Ne and O abundances of the ISM predicted by the CEM of the Milky Way of Medina-Amayo (2023). The dotted red line represents the mean value of log(Ne/O). The black dashed lines and the grey bands show the solar 12+log(Ne/H) and log(Ne/O) and their associated uncertainties, respectively, from Asplund et al. (2021).