Left: dice coefficient (as defined by Eq. (9)) of the top n% voxels between the 3D simulation cubes and their inferred counterparts in increments of 5% (yellow). The inner dark yellow layer represents the measure uncertainty, and the outer yellow layer represents the standard deviation over the set. The random overlap is represented in black. Right, red: dice coefficient significance (see Eq. (11)). Blue: Normalized Dice coefficient (see Eq. (10)). The coefficients are represented with their standard deviation layers.