Top: time series of the ESPRESSO RVs for HD 5278. Center: GLS periodogram of the original RV time series. Bottom: GLS periodogram of the residuals after removal of a sinusoid with a 41-day period. The vertical dashed line in the central and lower panels shows the period of the transiting planet candidate from TESS photometry. In the center and bottom panels, the horizontal long-dashed, dashed-dotted, and dotted lines represent 10%, 1%, and 0.1% FAP levels, respectively.