Relationship between the SFR and the stellar mass (main sequence) derived for the Herschel Reference Survey (HRS) late-type galaxies by Boselli et al. (2015). Filled dots are for HI-normal field galaxies, empty symbols for HI-deficient Virgo cluster objects. The large filled blue and empty red circles give the mean values in differentbins of stellar mass. The large green filled dots indicates the mean values of Gavazzi et al. (2015). The solid black and red lines are the bisector fit for HI-normal and HI-deficient galaxies, while the dotted lines are the linear fits. The linear best fit of Peng et al. (2010) is shown by the green dotted-dashed line, while that of Ciesla et al. (2014) by the yellow dashed line. The error bar in the lower right corner shows the typical uncertainty on the data (adapted from Boselli et al. 2015). The detection limit of VESTIGE will be ≃10⁻⁵ M_⊙ yr⁻¹. Red triangles indicate the extraplanar HII regions of NGC 4254 (M99) detected by VESTIGE and formed after a gravitational perturbation with a nearby object (paper III).