Same as Fig. 13 in Garrod et al. (2022), but for HC₅N, CH₃SH, and OCS. It shows the net rate of change in the COM’s abundances, summed over all chemical phases, during the cold collapse phase and the subsequent slow warm-up. Green represents a net production of the molecule, blue a net destruction. The time axis is divided into several phases marked with different background colours that are associated with the temperature ranges labelled in the right panels. The dotted black line marks the start of the warm-up phase, the two dashed lines indicate the time of thermal desorption of water.