Table A.1.
Two-tailed p-values for relative homology obtained from parametric (Mahalanobis distance) and non-parametric (Tukey depth) tests, for four mask binarization thresholds.
Relative homology | Relative homology | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mahalanobis | Tukey Depth | Mahalanobis | Tukey Depth | ||||||||||||
Resolution | Method | b0 | b1 | ECrel | b0 | b1 | ECrel | Resolution | Method | b0 | b1 | ECrel | b0 | b1 | ECrel |
Threshold = 0.70 | Threshold = 0.80 | ||||||||||||||
1024 | NILC | 0.236 | 0.244 | 0.472 | <0.001 | <0.001 | 0.302 | 1024 | NILC | 0.225 | 0.278 | 0.472 | <0.001 | <0.001 | 0.410 |
C-R | 0.048 | 0.170 | 0.130 | <0.001 | <0.001 | <0.001 | C-R | 0.048 | 0.169 | 0.130 | <0.001 | <0.001 | <0.001 | ||
SEVEM | <0.001 | <0.001 | 0.124 | <0.001 | <0.001 | <0.001 | SEVEM | <0.001 | <0.001 | 0.095 | <0.001 | <0.001 | <0.001 | ||
SMICA | <0.001 | 0.001 | 0.208 | <0.001 | <0.001 | <0.001 | SMICA | <0.001 | 0.002 | 0.217 | <0.001 | <0.001 | <0.001 | ||
512 | NILC | 0.492 | 0.325 | 0.666 | 0.134 | <0.001 | 0.685 | 512 | NILC | 0.499 | 0.348 | 0.686 | 0.130 | <0.001 | 0.649 |
C-R | 0.276 | 0.487 | 0.661 | <0.001 | <0.001 | 0.530 | C-R | 0.289 | 0.491 | 0.690 | <0.001 | <0.001 | 0.537 | ||
SEVEM | 0.660 | 0.303 | 0.751 | 0.389 | <0.001 | 0.586 | SEVEM | 0.657 | 0.362 | 0.813 | 0.268 | <0.001 | 0.649 | ||
SMICA | 0.478 | 0.472 | 0.908 | 0.134 | <0.001 | 0.870 | SMICA | 0.463 | 0.522 | 0.919 | 0.130 | <0.001 | 0.784 | ||
256 | NILC | 0.602 | 0.513 | 0.760 | 0.201 | 0.211 | 0.579 | 256 | NILC | 0.559 | 0.481 | 0.679 | 0.139 | 0.218 | 0.538 |
C-R | 0.518 | 0.635 | 0.750 | 0.259 | 0.353 | 0.579 | C-R | 0.541 | 0.631 | 0.752 | 0.139 | 0.380 | 0.604 | ||
SEVEM | 0.390 | 0.490 | 0.496 | 0.136 | 0.211 | 0.313 | SEVEM | 0.377 | 0.512 | 0.503 | 0.139 | 0.149 | 0.334 | ||
SMICA | 0.480 | 0.571 | 0.695 | 0.136 | 0.211 | 0.313 | SMICA | 0.459 | 0.562 | 0.723 | 0.139 | 0.218 | 0.604 | ||
128 | NILC | 0.260 | 0.441 | 0.627 | <0.001 | 0.171 | 0.327 | 128 | NILC | 0.295 | 0.484 | 0.633 | <0.001 | <0.001 | 0.331 |
C-R | 0.331 | 0.547 | 0.705 | 0.152 | 0.171 | 0.451 | C-R | 0.363 | 0.609 | 0.695 | <0.001 | 0.149 | 0.434 | ||
SEVEM | 0.399 | 0.543 | 0.807 | 0.152 | 0.222 | 0.630 | SEVEM | 0.318 | 0.640 | 0.755 | <0.001 | 0.149 | 0.517 | ||
SMICA | 0.383 | 0.564 | 0.763 | 0.232 | 0.171 | 0.524 | SMICA | 0.370 | 0.637 | 0.735 | <0.001 | <0.001 | 0.517 | ||
64 | NILC | 0.335 | 0.278 | 0.528 | 0.171 | <0.001 | <0.001 | 64 | NILC | 0.250 | 0.269 | 0.382 | <0.001 | <0.001 | <0.001 |
C-R | 0.319 | 0.366 | 0.528 | 0.237 | <0.001 | 0.314 | C-R | 0.192 | 0.363 | 0.438 | <0.001 | <0.001 | 0.311 | ||
SEVEM | 0.211 | 0.352 | 0.488 | <0.001 | <0.001 | <0.001 | SEVEM | 0.166 | 0.336 | 0.408 | <0.001 | <0.001 | 0.311 | ||
SMICA | 0.259 | 0.306 | 0.448 | <0.001 | <0.001 | <0.001 | SMICA | 0.172 | 0.339 | 0.351 | <0.001 | <0.001 | 0.000 | ||
32 | NILC | 0.082 | 0.302 | 0.442 | <0.001 | <0.001 | <0.001 | 32 | NILC | 0.082 | 0.406 | 0.538 | <0.001 | <0.001 | <0.001 |
C-R | 0.166 | 0.292 | 0.509 | <0.001 | 0.252 | <0.001 | C-R | 0.149 | 0.452 | 0.707 | <0.001 | 0.345 | 0.652 | ||
SEVEM | 0.160 | 0.444 | 0.704 | <0.001 | 0.252 | 0.351 | SEVEM | 0.175 | 0.515 | 0.774 | <0.001 | 0.292 | 0.810 | ||
SMICA | 0.155 | 0.294 | 0.472 | <0.001 | <0.001 | 0.351 | SMICA | 0.133 | 0.384 | 0.578 | <0.001 | 0.292 | 0.607 | ||
16 | NILC | 0.018 | 0.030 | 0.120 | <0.001 | <0.001 | <0.001 | 16 | NILC | 0.024 | 0.043 | 0.082 | <0.001 | <0.001 | <0.001 |
C-R | 0.032 | 0.016 | 0.102 | <0.001 | <0.001 | <0.001 | C-R | 0.028 | 0.042 | 0.119 | <0.001 | <0.001 | <0.001 | ||
SEVEM | 0.037 | 0.016 | 0.178 | <0.001 | <0.001 | <0.001 | SEVEM | 0.064 | 0.024 | 0.119 | <0.001 | <0.001 | <0.001 | ||
SMICA | 0.017 | 0.001 | 0.021 | <0.001 | <0.001 | <0.001 | SMICA | 0.039 | 0.007 | 0.046 | <0.001 | <0.001 | <0.001 | ||
8 | NILC | 0.373 | <0.001 | 0.012 | 0.430 | <0.001 | <0.001 | 8 | NILC | 0.202 | <0.001 | 0.013 | 0.142 | <0.001 | 0.220 |
C-R | 0.706 | <0.001 | 0.022 | 0.693 | 0.108 | <0.001 | C-R | 0.573 | <0.001 | 0.013 | 0.599 | <0.001 | <0.001 | ||
SEVEM | 0.546 | <0.001 | 0.009 | 0.563 | <0.001 | <0.001 | SEVEM | 0.352 | <0.001 | 0.012 | 0.358 | <0.001 | <0.001 | ||
SMICA | 0.401 | <0.001 | 0.004 | 0.380 | <0.001 | <0.001 | SMICA | 0.331 | <0.001 | 0.012 | 0.323 | <0.001 | <0.001 | ||
Summary | NILC | 0.002 | 0.001 | 0.002 | <0.001 | <0.001 | <0.001 | Summary | NILC | 0.001 | 0.001 | 0.002 | <0.001 | 0.032 | <0.001 |
C-R | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | C-R | 0.001 | 0.001 | 0.001 | 0.001 | 0.032 | 0.001 | ||
SEVEM | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | SEVEM | 0.001 | 0.001 | 0.001 | 0.001 | 0.032 | 0.001 | ||
SMICA | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | SMICA | 0.001 | 0.001 | 0.001 | 0.001 | 0.032 | 0.001 | ||
Threshold = 0.90 | Threshold = 0.95 | ||||||||||||||
1024 | NILC | 0.225 | 0.278 | 0.472 | <0.001 | <0.001 | 0.410 | 1024 | NILC | 0.225 | 0.278 | 0.472 | <0.001 | <0.001 | 0.410 |
C-R | <0.001 | 0.169 | 0.130 | <0.001 | <0.001 | <0.001 | C-R | 0.048 | 0.169 | 0.130 | <0.001 | <0.001 | <0.001 | ||
SEVEM | <0.001 | <0.001 | 0.095 | <0.001 | <0.001 | <0.001 | SEVEM | <0.001 | <0.001 | 0.095 | <0.001 | <0.001 | <0.001 | ||
SMICA | <0.001 | <0.001 | 0.217 | <0.001 | <0.001 | <0.001 | SMICA | <0.001 | 0.002 | 0.217 | <0.001 | <0.001 | <0.001 | ||
512 | NILC | 0.526 | 0.340 | 0.661 | 0.264 | <0.001 | 0.641 | 512 | NILC | 0.531 | 0.340 | 0.654 | 0.207 | <0.001 | 0.445 |
C-R | 0.307 | 0.484 | 0.673 | <0.001 | <0.001 | 0.596 | C-R | 0.322 | 0.462 | 0.664 | <0.001 | <0.001 | 0.445 | ||
SEVEM | 0.645 | 0.389 | 0.809 | 0.414 | <0.001 | 0.685 | SEVEM | 0.606 | 0.403 | 0.803 | 0.262 | <0.001 | 0.530 | ||
SMICA | 0.465 | 0.517 | 0.906 | 0.132 | 0.139 | 0.685 | SMICA | 0.454 | 0.540 | 0.896 | 0.207 | 0.134 | 0.592 | ||
256 | NILC | 0.601 | 0.584 | 0.738 | 0.150 | 0.306 | 0.589 | 256 | NILC | 0.602 | 0.550 | 0.702 | 0.139 | 0.345 | 0.434 |
C-R | 0.529 | 0.675 | 0.754 | 0.271 | 0.385 | 0.589 | C-R | 0.547 | 0.620 | 0.739 | 0.139 | 0.274 | 0.434 | ||
SEVEM | 0.326 | 0.525 | 0.509 | 0.150 | 0.150 | <0.001 | SEVEM | 0.342 | 0.504 | 0.521 | 0.139 | 0.000 | 0.316 | ||
SMICA | 0.437 | 0.633 | 0.724 | 0.150 | 0.214 | 0.589 | SMICA | 0.482 | 0.658 | 0.734 | 0.215 | 0.380 | 0.511 | ||
128 | NILC | 0.259 | 0.525 | 0.486 | <0.001 | 0.160 | <0.001 | 128 | NILC | 0.309 | 0.524 | 0.554 | <0.001 | 0.165 | 0.446 |
C-R | 0.355 | 0.605 | 0.614 | 0.180 | 0.238 | <0.001 | C-R | 0.313 | 0.601 | 0.612 | 0.169 | 0.165 | 0.530 | ||
SEVEM | 0.275 | 0.681 | 0.683 | <0.001 | 0.160 | 0.344 | SEVEM | 0.381 | 0.624 | 0.795 | 0.169 | 0.237 | 0.674 | ||
SMICA | 0.250 | 0.617 | 0.528 | <0.001 | 0.160 | <0.001 | SMICA | 0.308 | 0.597 | 0.563 | <0.001 | 0.237 | 0.446 | ||
64 | NILC | 0.611 | 0.248 | 0.444 | 0.547 | <0.001 | 0.428 | 64 | NILC | 0.420 | 0.157 | 0.430 | 0.276 | <0.001 | <0.001 |
C-R | 0.571 | 0.369 | 0.651 | 0.426 | <0.001 | 0.428 | C-R | 0.491 | 0.125 | 0.440 | 0.319 | <0.001 | <0.001 | ||
SEVEM | 0.597 | 0.336 | 0.630 | 0.559 | <0.001 | 0.663 | SEVEM | 0.466 | 0.082 | 0.292 | 0.276 | <0.001 | <0.001 | ||
SMICA | 0.430 | 0.348 | 0.458 | 0.397 | <0.001 | 0.307 | SMICA | 0.438 | 0.111 | 0.259 | 0.276 | <0.001 | <0.001 | ||
32 | NILC | 0.053 | 0.305 | 0.300 | <0.001 | 0.243 | 0.340 | 32 | NILC | 0.076 | 0.246 | 0.174 | <0.001 | <0.001 | <0.001 |
C-R | 0.248 | 0.633 | 0.754 | 0.190 | 0.441 | 0.700 | C-R | 0.375 | 0.513 | 0.767 | 0.356 | 0.342 | 0.715 | ||
SEVEM | 0.175 | 0.638 | 0.715 | <0.001 | 0.370 | 0.585 | SEVEM | 0.217 | 0.493 | 0.634 | <0.001 | 0.166 | 0.522 | ||
SMICA | 0.141 | 0.389 | 0.514 | <0.001 | 0.333 | 0.531 | SMICA | 0.107 | 0.367 | 0.431 | <0.001 | <0.001 | <0.001 | ||
16 | NILC | 0.009 | 0.054 | 0.081 | <0.001 | <0.001 | <0.001 | 16 | NILC | 0.436 | 0.016 | 0.027 | 0.383 | <0.001 | <0.001 |
C-R | 0.026 | 0.038 | 0.087 | <0.001 | <0.001 | <0.001 | C-R | 0.358 | 0.007 | 0.022 | 0.339 | <0.001 | <0.001 | ||
SEVEM | 0.024 | 0.025 | 0.055 | <0.001 | <0.001 | <0.001 | SEVEM | 0.582 | 0.020 | 0.021 | 0.562 | <0.001 | <0.001 | ||
SMICA | 0.013 | 0.014 | 0.081 | <0.001 | <0.001 | <0.001 | SMICA | 0.353 | 0.012 | 0.062 | 0.339 | <0.001 | <0.001 | ||
8 | NILC | 0.408 | <0.001 | 0.007 | 0.401 | <0.001 | <0.001 | 8 | NILC | 0.871 | 0.047 | 0.188 | 0.846 | <0.001 | 0.517 |
C-R | 0.610 | <0.001 | 0.023 | 0.568 | <0.001 | 0.330 | C-R | 0.773 | 0.144 | 0.384 | 0.525 | 0.160 | 0.611 | ||
SEVEM | 0.502 | <0.001 | 0.012 | 0.528 | <0.001 | 0.237 | SEVEM | 0.735 | 0.104 | 0.265 | 0.451 | <0.001 | 0.564 | ||
SMICA | 0.414 | <0.001 | 0.014 | 0.455 | <0.001 | <0.001 | SMICA | 0.887 | 0.081 | 0.181 | 0.816 | 0.195 | 0.466 | ||
Summary | NILC | 0.010 | <0.001 | 0.001 | <0.001 | 0.002 | <0.001 | Summary | NILC | 0.213 | 0.003 | 0.010 | <0.001 | 0.009 | 0.001 |
C-R | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | C-R | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 | ||
SEVEM | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | SEVEM | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 | ||
SMICA | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | SEVEM | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 |
Notes. The last entry for each threshold is the p-value for the summary statistic computed across all resolutions. Marked in boldface are p-values of 0.05 or smaller.
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