values calculated for the current (uppermost panel) and next-generation (middle panel) instruments, for different exposure times as functions of energy and of the angular extension (lowermost panel). In the two upper plots, the curves refer to the point-source hypothesis (dash-dotted lines) and to a 0.5°-wide source (solid lines). The percentage of the MD16 clouds that overcome an value of 0.05, 0.3, and 1, assuming the local CR spectrum, is indicated in the figure. As a reference, the values of Aquila rift (AqR) and Sagittarius B2 (SgrB) are also plotted. Those were computed from the spectra reported in Baghmanyan et al. (2020) and Aharonian et al. (2020), respectively. In the lowermost panel, the physical properties (A, θ) of the MCsof the MD16 catalog are compared to the detection thresholds of the considered gamma instruments, (see Eq. (7)). The same exposure as in the upper panels is assumed.