Maps of selected HRA regions with NESTs. Grey dots represent the YSOs in the area, and coloured markers show the position of NESTs. Symbols indicate whether the activity of NESTs is significantly different (triangles for larger and inverted triangles for lower activity) or consistent with the average (circles). The colour-scale shows the ratio of Class 0/I objects assigned to each NEST. Contours show each region’s relative-risk map values, and red contours mark the threshold boundaries, f̄_C0/I ± σ_fC0/I, separating areas with values different from the average control distribution for each region (solid red contour for the upper limit and dashed red contour for the lower limit).